Mouse pneumonectomy model of compensatory lung growth

S Liu, J Cimprich, BM Varisco - JoVE (Journal of Visualized Experiments), 2014 - jove.com
In humans, disrupted repair and remodeling of injured lung contributes to a host of acute
and chronic lung disorders which may ultimately lead to disability or death. Injury-based
animal models of lung repair and regeneration are limited by injury-specific responses
making it difficult to differentiate changes related to the injury response and injury resolution
from changes related to lung repair and lung regeneration. However, use of animal models
to identify these repair and regeneration signaling pathways is critical to the development of …