A novel operant method testing acute cold hypersensitivity in mice using a modification of the Coy Mechanical Conflict-Avoidance System™
S Zhou, S Carlton - The Journal of Pain, 2012 - jpain.org
Subliminal stimulation of the motor cortex has been used to treat patients with neuropathic
pain resistant to other conventional treatments. Data obtained by our group demonstrates
that transdural electrical stimulation of the motor cortex (MCS) induces opioid-dependent
analgesia in normal or neuropathic rats evaluated by the paw pressure test. This study
aimed to investigate the possible topography involved in this effect as well as the pattern of
neuronal activation, evaluated by Fos and Zif268 immunolabel, was performed in the spinal …
pain resistant to other conventional treatments. Data obtained by our group demonstrates
that transdural electrical stimulation of the motor cortex (MCS) induces opioid-dependent
analgesia in normal or neuropathic rats evaluated by the paw pressure test. This study
aimed to investigate the possible topography involved in this effect as well as the pattern of
neuronal activation, evaluated by Fos and Zif268 immunolabel, was performed in the spinal …
