[HTML][HTML] Neuroprotective effect of interleukin-6 regulation of voltage-gated Na+ channels of cortical neurons is time-and dose-dependent
W Xia, G Peng, J Sheng, F Zhu, J Guo… - Neural regeneration …, 2015 - journals.lww.com
Interleukin-6 has been shown to be involved in nerve injury and nerve regeneration, but the
effects of long-term administration of high concentrations of interleukin-6 on neurons in the
central nervous system is poorly understood. This study investigated the effects of 24 hour
exposure of interleukin-6 on cortical neurons at various concentrations (0.1, 1, 5 and 10
ng/mL) and the effects of 10 ng/mL interleukin-6 exposure to cortical neurons for various
durations (2, 4, 8, 24 and 48 hours) by studying voltage-gated Na+ channels using a patch …
effects of long-term administration of high concentrations of interleukin-6 on neurons in the
central nervous system is poorly understood. This study investigated the effects of 24 hour
exposure of interleukin-6 on cortical neurons at various concentrations (0.1, 1, 5 and 10
ng/mL) and the effects of 10 ng/mL interleukin-6 exposure to cortical neurons for various
durations (2, 4, 8, 24 and 48 hours) by studying voltage-gated Na+ channels using a patch …
